“We always thought of cancer as a disease of the genome because it arises from DNA mutations, but it turns out it's just knowing the DNA won't get you to the answer. You need to know a lot more than the DNA, and in particular, you need to know a lot about proteins. And so we fast forward from you know, 2005 to 2023,18 years later, the total number of cancer patients that actually benefit from genomic sequencing their cancer and then matching them to a drug, it's about 10%, which is incredibly disappointing compared to where we were in 2005, thinking we were gonna get, you know, pushing 100%. And for the 10%, it's fantastic. When DNA sequencing and genomic medicine works, it's absolutely terrific. It just doesn't work enough of the time.”

“These doctors are so busy, in fact, that these front line sales organizations of these different companies, whether it's a startup or an established product, they're often one of the more valuable tools that the doctors have to stay abreast of the things that are going on. There are so many innovations and so many new drugs and new studies and all of these different things coming out all the time that your average community based oncologist who is seeing 30 patients a day with 25 different disease types – that's not even to begin the discussion of how different management of a newly diagnosed early stage breast cancer patient is compared to a patient with late stage leukemia. I mean, these are completely different diseases and are treated and managed and all of that differently. And so it's really challenging. I mean, it's impossible really for any one physician to keep up on all of those different things. And so that becomes a lot of the role of the sales team and the commercial side of the companies is to keep the physicians aware of these things that are sort of happening and changing.”

“Doctors are becoming more and more comfortable with their patients bringing them information. We live in an age of information that everything's available online, and AI tools are helping patients to find these things even better. But well-informed patients that are doing the reading, doing the research, doing the understanding, and they're taking things to their doctors with thoughtful, well-intentioned ideas about what they might be able to do to impact their own life. We're in a world where physicians, especially younger physicians that are coming out with this kind of experience, are becoming increasingly comfortable with that kind of patient interaction.”